Andrea Armirotti Selected Research

ARN22089

1/2022

Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer.

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Andrea Armirotti Research Topics

Disease

10	Inflammation (Inflammations) 02/2019 - 05/2012
9	Cystic Fibrosis (Mucoviscidosis) 01/2022 - 04/2011
7	Neoplasms (Cancer) 01/2022 - 01/2013
7	Pain (Aches) 11/2021 - 11/2011
5	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 10/2005
3	Huntington Disease (Huntington's Disease) 05/2018 - 01/2017
3	Hyperalgesia 09/2015 - 05/2012
2	Melanoma (Melanoma, Malignant) 01/2022 - 01/2017
2	Wounds and Injuries (Trauma) 01/2022 - 01/2016
2	Burns 01/2022 - 03/2016
2	Atrophy 01/2018 - 01/2017
2	Breast Neoplasms (Breast Cancer) 09/2014 - 07/2014
1	Schizophrenia (Dementia Praecox) 01/2022
1	Insulin Resistance 01/2022
1	Neuralgia (Stump Neuralgia) 11/2021
1	Sarcoma (Soft Tissue Sarcoma) 01/2021
1	Osteosarcoma (Osteogenic Sarcoma) 01/2021
1	Brain Neoplasms (Brain Tumor) 01/2021
1	Nervous System Diseases (Neurological Disorders) 01/2021
1	Neuroblastoma 12/2020
1	Leukemia 11/2020
1	Anxiety Disorders (Anxiety Disorder) 09/2020
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 09/2020
1	Feeding and Eating Disorders (Eating Disorder) 09/2020
1	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 09/2020
1	Autistic Disorder (Autism) 08/2020
1	Down Syndrome (Down's Syndrome) 08/2020
1	Brain Diseases (Brain Disorder) 08/2020
1	Gliosis 01/2020
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2020
1	Starvation 01/2020
1	Alcoholism (Alcohol Abuse) 01/2020

Drug/Important Bio-Agent (IBA)

9	LipidsIBA 11/2021 - 01/2013
6	Pharmaceutical PreparationsIBA 01/2022 - 03/2009
5	Biomarkers (Surrogate Marker)IBA 01/2021 - 10/2017
4	Analgesics (Analgesic Drugs)IBA 11/2021 - 11/2011
4	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 07/2020 - 04/2011
3	SphingolipidsIBA 01/2022 - 01/2017
3	AcidsIBA 01/2021 - 08/2015
3	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2021 - 01/2017
3	EnzymesIBA 11/2020 - 03/2009
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 09/2014
3	CeramidesIBA 01/2019 - 01/2013
3	Phenylalanine (L-Phenylalanine)FDA Link 01/2019 - 01/2018
3	amidaseIBA 01/2018 - 01/2013
3	palmidrolIBA 01/2018 - 08/2015
3	Chloride Channels (Chloride Channel)IBA 01/2018 - 04/2011
3	anandamide (arachidonylethanolamide)IBA 02/2016 - 11/2011
2	AlginatesIBA 01/2022 - 03/2016
2	ChloridesIBA 01/2021 - 01/2018
2	PoisonsIBA 11/2020 - 01/2020
2	AnionsIBA 01/2019 - 01/2018
2	ThymosinIBA 01/2019 - 01/2018
2	Ligases (Synthetase)IBA 01/2018 - 07/2015
2	UbiquitinIBA 01/2018 - 07/2015
2	5-phenylpentyl N- ((2S,3R)- 2- methyl- 4- oxo- oxetan- 3- yl)carbamateIBA 01/2018 - 09/2013
2	N-acylethanolaminesIBA 01/2018 - 08/2015
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2018 - 08/2015
2	Acid CeramidaseIBA 01/2017 - 01/2013
2	EndocannabinoidsIBA 02/2016 - 06/2015
2	oleoylethanolamideIBA 01/2016 - 08/2015
2	ErbB Receptors (EGF Receptor)IBA 01/2016 - 07/2014
2	Adenosine Triphosphate (ATP)IBA 11/2015 - 09/2014
2	temsirolimus FDA Link 08/2009 - 12/2008
2	Amyloid beta-PeptidesIBA 10/2007 - 10/2005
1	Free RadicalsIBA 01/2022
1	Olive OilIBA 01/2022
1	Palm OilIBA 01/2022
1	Antipsychotic Agents (Antipsychotics)IBA 01/2022
1	AntioxidantsIBA 01/2022
1	GTP Phosphohydrolases (GTPases)IBA 01/2022
1	ARN22089IBA 01/2022
1	lumacaftorIBA 01/2022
1	Clozapine (Clozaril)FDA LinkGeneric 01/2022
1	Phosphates (Orthophosphate)IBA 11/2021
1	Phosphatidic Acids (Phosphatidic Acid)IBA 11/2021
1	lysophosphatidic acidIBA 11/2021
1	muramyl- NAc- (pentapeptide)pyrophosphoryl- undecaprenolIBA 11/2021
1	Peptidoglycan (Murein)IBA 11/2021
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2021
1	Serine (L-Serine)FDA Link 01/2021
1	Fingolimod Hydrochloride (FTY720)FDA Link 01/2021
1	Diclofenac (SR 38)FDA LinkGeneric 01/2021
1	Docetaxel (Taxotere)FDA Link 01/2021
1	OxazolesIBA 12/2020
1	Antidepressive Agents (Antidepressants)IBA 09/2020
1	DiureticsIBA 08/2020
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2020
1	benzoxazoloneIBA 01/2020
1	Protein Phosphatase 1IBA 01/2020
1	gamma-Aminobutyric Acid (GABA)IBA 01/2020
1	piperidineIBA 01/2020
1	Glutamic Acid (Glutamate)FDA Link 01/2020
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020

Therapy/Procedure

2	Oral Administration 12/2020 - 06/2015
2	Topical Administration 09/2015 - 09/2013
2	Renal Dialysis (Hemodialysis) 08/2009 - 12/2008
1	Drug Therapy (Chemotherapy) 01/2021
1	Transcranial Magnetic Stimulation 01/2020